ARG83253
Human CHRDL2 ELISA Kit
Human CHRDL2 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83253 Human CHRDL2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CHRDL2 in Serum, Plasma and Cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | CHRDL2 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 13 pg/ml |
| Detection Range | 93.7 pg/ml - 6,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 5.0% Inter-Assay CV: 4.7% |
| Alternate Names | CHRDL2; Chordin Like 2; BNF1; Breast Tumor Novel Factor 1; Chordin-Related Protein 2; Chordin-Like Protein 2; CHL2; BNF-1 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CHRDL2 |
| Gene Full Name | Chordin Like 2 |
| Background | This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. |
| Function | May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. |
| Cellular Localization | Cytoplasm, Secreted |
| PTM | Glycoprotein, Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG83253 Human CHRDL2 ELISA Kit standard curve image
ARG83253 Human CHRDL2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83253 Human CHRDL2 ELISA Kit User manual |
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