ARG30315
Brain Injury IHC Marker Antibody Duo (GFAP, MMP9)
Publication12
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG22191 | anti-MMP9 antibody [SB15c] | Mouse mAb | Hu | ELISA, ICC/IF, IHC-P, WB | 50 μg |
| ARG10122 | anti-GFAP antibody [GF5] | Mouse mAb | Hu, Ms, Rat | ELISA, ICC/IF, IHC-Fr, WB | 50 μg |
Overview
| Product Description | Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in mature astrocytes, a main type of glial cells in the central nervous system (CNS). GFAP is augmented in astrogliosis, a pathophysiology associated with degenerative and infectious/inflammatory brain disorders. Matrix metalloproteinase 9 (MMP-9) is a member of metalloproteinases family. It cleaves ECM and cell surface receptors allowing for synaptic and circuit level reorganization. MMP-9 level is increased after traumatic brain injury and involved in the following excitotoxic neuronal loss. arigo's ARG30292 Brain Injury IHC Marker Antibody Duo (GFAP, MMP9) comprise two antibodies against GFAP and MMP9, the pathological hallmark of CNS lesions, and is excellent for histological analysis of brain injury. Related news: Astrocyte-to-neuron conversion for Parkinson's disease treatment |
|---|---|
| Target Name | Brain Injury IHC Marker |
| Alternate Names | Brain Injury IHC Marker antibody; GFAP antibody; MMP9 antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Images (6) Click the Picture to Zoom In
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ARG10122 anti-GFAP antibody [GF5] ICC/IF image
Immunofluorescence: Rat astrocyte primary cell stained with ARG10122 anti-GFAP antibody [GF5] (green) at 1:200 dilution.
Cell nuclei was stained with DAPI (blue). -
ARG10122 anti-GFAP antibody [GF5] IHC-Fr image
Immunohistochemistry: Rat ventral horn of spinal cord stained with ARG10122 anti-GFAP antibody [GF5] at 1: 500 dilution.
From Chin-An Chen et al. Int J Med Sci. (2021), doi: 10.7150/ijms.65976, Fig. 4A.
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ARG10122 anti-GFAP antibody [GF5] WB image
Western blot: 20 µg of Mouse brain and Rat brain lysates stained with ARG10122 anti-GFAP antibody [GF5] at 1:500 dilution.
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ARG22191 anti-MMP9 antibody [SB15c] IHC-P image
Immunohistochemistry: Paraffin-embedded Human gastric cancer tissue stained with ARG21961 Mouse IgG2a Isotype Control antibody [HOPC-1] (left) and ARG22191 anti-MMP9 antibody [SB15c] (right) followed by ARG23705 Goat anti-Mouse IgG2a (HRP) (pre-adsorbed), DAB and hematoxylin.
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ARG10122 anti-GFAP antibody [GF5] WB image
Western blot: 30 µg of Rat brain lysate stained with ARG10122 anti-GFAP antibody [GF5] at 1:500 dilution.
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Specific References
Norepinephrine-Activated p38 MAPK Pathway Mediates Stress-Induced Cytotoxic Edema of Basolateral Amygdala Astrocytes
ARG10122: WB, IHC-P, ICC/IF / Rat
Magnetic stirring with iron oxide nanospinners accretes neurotoxic Aβ42 oligomers into phagocytic clearable plaques for Alzheimer's disease treatment
ARG10122: IHC-Fr / Mouse
SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells
ARG10122: WB / Mouse
Secreted Neutrophil Gelatinase-Associated Lipocalin Shows Stronger Ability to Inhibit Cyst Enlargement of ADPKD Cells Compared with Nonsecreted Form
ARG10122: WB / Mouse
SCM-198 Prevents Endometriosis By Reversing Low Autophagy Levels Of Endometriotic Stromal Cells Via Inhibiting TNF-Α-Aromatase-Estrogen-Erα Pathway And Promoting PR Expression
ARG10122: WB / Human
Effects of Chronic Restraint Stress on Apoptosis of Amygdala Cells in Rats
ARG10122: IHC-P / Rat
SCM-198 ameliorates endometrial inflammation via suppressing the LPS-JNK-cJUN/cFOS-TLR4-NF-κB pathway
ARG10122: WB / Human
Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy
ARG10122: IHC-Fr / Rat
RIP3/MLKL pathway-regulated necroptosis: A new mechanism of paclitaxel-induced peripheral neuropathy
ARG10122: IHC-Fr / Rat
Mechanisms of bupivacaine inhibition of glutamate-induced intracellular calcium elevation in primary cultured rat hippocampal astrocytes.
ARG10122: ICC/IF / Rat
Hsa_circ_0091074 regulates TAZ expression via microRNA‑1297 in triple negative breast cancer cells.
ARG22191 /
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
ARG10122: WB, IF, IHC-Fr / Rat
