ARG10205
anti-serum Amyloid A antibody [607] (HRP)
anti-serum Amyloid A antibody [607] (HRP) for ELISA and Human
Cell Biology and Cellular Response antibody; Metabolism antibody
Overview
| Product Description | HRP-conjugated Mouse Monoclonal antibody [607] recognizes Human serum Amyloid A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, TGF-β and EGF. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 607 |
| Isotype | IgG2a, kappa |
| Target Name | serum Amyloid A |
| Antigen Species | Human |
| Immunogen | Highly purified recombinant human serum Amyloid A (MW: 12 kDa) |
| Conjugation | HRP |
| Alternate Names | 2-104; 2-103; 2-102; Serum amyloid A-1 protein; TP53I4; SAA; Amyloid fibril protein AA; SAA2; PIG4; 4-101; 3-104 |
Application Instructions
| Application Note | ELISA: This HRP conjugated antibody can be used as a detection antibody in sandwich ELISA applications for human SAA detection. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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Properties
| Form | Liquid |
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| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.2) and 50% Glycerol |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SAA1 |
| Gene Full Name | serum amyloid A1 |
| Background | SAA is an acute phase protein and a sensitive inflammatory marker. Cytokines such as IL-1, IL-6 and TNF-alpha stimulates hepatocytes to produce and release SAA. In acute phase, SAA in blood can increase to more than 1,000 folds of normal level. Prolonged and repeated elevation of SAA results in abnormal deposition of amyloid proteins in organ or tissue in insoluble beta pleated form. Determination of SAA levels is important for assessment of renal allograft rejection, estimation of tissue damage caused by myocardial infarction and severe angina, and diagnosis of inflammation in cystic fibrosis patients and in patients infected with virus. |
| Function | Major acute phase protein. [UniProt] |
| Highlight | Related Antibody Duos and Panels: ARG30077 serum Amyloid A ELISA Antibody Duo Related products: serum Amyloid A antibodies; serum Amyloid A ELISA Kits; serum Amyloid A Duos / Panels; Anti-Mouse IgG secondary antibodies; |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody |
| Calculated MW | 14 kDa |
| PTM | This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. |
