ARG54677
anti-p19 INK4d antibody
anti-p19 INK4d antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes p19 INK4d |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | p19 INK4d |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide within 15-43 aa (N-terminus) of Human p19 INK4d protein (NP_001791.1). |
| Conjugation | Un-conjugated |
| Alternate Names | p19-INK4D; p19; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; INK4D |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse testis |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P55273 Human Cyclin-dependent kinase 4 inhibitor D Swiss-port # Q60773 Mouse Cyclin-dependent kinase 4 inhibitor D |
|---|---|
| Gene Symbol | CDKN2D |
| Gene Full Name | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| Background | P19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
| Cellular Localization | Nucleus, Cytoplasm |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| Calculated MW | 18 kDa |
Images (3) Click the Picture to Zoom In
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ARG54677 anti-p19 INK4d antibody IHC image
Immunohistochemistry: Formalin fixed and paraffin embedded testis tissue stained with ARG54677 anti-p19 INK4d antibody.
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ARG54677 anti-p19 INK4d antibody WB image
Western blot: 35 µg of Mouse testis lysate stained with ARG54677 anti-p19 INK4d antibody.
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ARG54677 anti-p19 INK4d antibody FACS image
Flow Cytometry: HeLa cells stained with ARG54677 anti-p19 INK4d antibody (right histogram) or without primary antibody control (left histogram).
