ARG64567
anti-mKIAA0319 antibody
anti-mKIAA0319 antibody for Western blot and Mouse
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes mKIAA0319 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Rat |
| Tested Application | WB |
| Specificity | The variants XP_341528.2 and XP_001070349.1 represent identical protein. This antibody is expected to cross-react with mouse KIAA0319 isoform 1 (NP_001074520.1), isoform 2 (XP_994023.1) and isoform 4 (XP_913491.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | mKIAA0319 |
| Antigen Species | Mouse |
| Immunogen | C-QGKIKQENKPTLH |
| Conjugation | Un-conjugated |
| Alternate Names | Dyslexia-associated protein KIAA0319; DYX2; DYLX2; NMIG |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | D130043K22Rik |
|---|---|
| Gene Full Name | RIKEN cDNA D130043K22 gene |
| Background | This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in a similar gene in human are associated with dyslexia. Alternatively spliced transcript variants have been identifed. [provided by RefSeq, May 2015] |
| Function | Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites (By similarity). [UniProt] |
| Research Area | Neuroscience antibody |
| Calculated MW | 118 kDa |
| PTM | N-glycosylated. O-glycosylated. Shedding of the extracellular domain and intramembrane cleavage produce several proteolytic products. The intramembrane cleavage releases a soluble cytoplasmic polypeptide that translocates to the nucleolus. |
Images (1) Click the Picture to Zoom In
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ARG64567 anti-mKIAA0319 antibody WB image
Western Blot: Mouse Brain lysate (35 µg protein in RIPA buffer) stained with ARG64567 anti-mKIAA0319 antibody at 0.5 µg/ml dilution.
