ARG59704
anti-hemoglobin gamma antibody
anti-hemoglobin gamma antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes hemoglobin gamma |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody react to hemoglobin subunit gamma 1 and gamma 2. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | hemoglobin gamma |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human hemoglobin gamma. |
| Conjugation | Un-conjugated |
| Alternate Names | Hemoglobin gamma-1 chain; HBGR; HSGGL1; PRO2979; Hemoglobin subunit gamma-1; HBG-T2; Hemoglobin gamma-A chain; Gamma-1-globin; HBGA; Hb F Agamma |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 11 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HBG1 |
| Gene Full Name | hemoglobin, gamma A |
| Background | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] |
| Function | Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. [UniProt] |
| Calculated MW | 16 kDa |
| PTM | Acetylation of Gly-2 converts Hb F to the minor Hb F1. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59704 anti-hemoglobin gamma antibody WB image
Western blot: K562 cell lysate stained with ARG59704 anti-hemoglobin gamma antibody.
