ARG54899

anti-beta NGF antibody

anti-beta NGF antibody for Western blot and Mouse

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes beta NGF
Tested Reactivity Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name beta NGF
Antigen Species Human
Immunogen Recombinant protein of Human beta NGF.
Conjugation Un-conjugated
Alternate Names HSAN5; Beta-nerve growth factor; Beta-NGF; NGFB

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse liver and HeLa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 18049 Mouse NGF

Swiss-port # P01139 Mouse Beta-nerve growth factor

Gene Symbol NGF
Gene Full Name nerve growth factor (beta polypeptide)
Background This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. [UniProt]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 27 kDa

Images (1) Click the Picture to Zoom In

  • ARG54899 anti-beta NGF antibody WB image

    Western blot: Mouse liver and HeLa cell lysates stained with ARG54899 anti-beta NGF antibody.