ARG44621
anti-alpha 1 microglobulin antibody
anti-alpha 1 microglobulin antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes alpha 1 microglobulin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | alpha 1 microglobulin |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | AMBP; Alpha-1-Microglobulin/Bikunin Precursor; HCP; Protein HC; IATIL; ITILC; EDC1; HI30; ITIL; UTI; Complex-Forming Glycoprotein Heterogeneous In Charge; Inter-Alpha-Trypsin Inhibitor Light Chain; Growth-Inhibiting Protein 19; Uronic-Acid-Rich Protein; Protein AMBP; Trypstatin; Uristatin; Bikunin; ITI; A1M |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | AMBP |
| Gene Full Name | Alpha-1-Microglobulin/Bikunin Precursor |
| Background | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008] |
| Function | Has a chaperone role in facilitating the correct folding of bikunin in the endoplasmic reticulum compartment. Also inhibits calcium oxalate crystallization. [UniProt] |
| Cellular Localization | Cell membrane, Cytoplasm, Endoplasmic reticulum, Extracellular matrix, Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleus, Secreted. [UniProt] |
| Calculated MW | 39 kDa |
| PTM | Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Proteoglycan. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG44621 anti-alpha 1 microglobulin antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44621 anti-alpha 1 microglobulin antibody at 2.5 µg/mL dilution.
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ARG44621 anti-alpha 1 microglobulin antibody WB image
Western blot: HepG2 stained with ARG44621 anti-alpha 1 microglobulin antibody at 1 µg/mL dilution.
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ARG44621 anti-alpha 1 microglobulin antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44621 anti-alpha 1 microglobulin antibody.
