Overview

Product Description	Goat Polyclonal antibody recognizes ZO1
Tested Reactivity	Hu
Tested Application	ICC/IF
Specificity	This antibody is expected to recognize both reported isoforms (NP_003248.3; NP_783297.2)
Host	Goat
Clonality	Polyclonal
Isotype	IgG
Target Name	ZO1
Antigen Species	Human
Immunogen	C-PKPTSQNQFSEHDKT
Conjugation	Un-conjugated
Alternate Names	Zonula occludens protein 1; Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; ZO-1

Application Instructions

Application Suggestion	Tested Application Dilution ICC/IF 10 -20 µg/ml
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer	Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative	0.02% Sodium azide
Stabilizer	0.5% BSA
Concentration	0.5 mg/ml
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 7082 Human TJP1 Swiss-port # Q07157 Human Tight junction protein ZO-1
Background	This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Research Area	Controls and Markers antibody
Calculated MW	195 kDa
PTM	Phosphorylated. Dephosphorylated by PTPRJ.

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