ARG44351
anti-XPNPEP3 antibody
anti-XPNPEP3 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes XPNPEP3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | XPNPEP3 |
| Antigen Species | Human |
| Immunogen | Human XPNPEP3 recombinant fusion protein (a.a. sequence: 1-250). |
| Conjugation | Un-conjugated |
| Alternate Names | XPNPEP3; X-Prolyl Aminopeptidase 3; APP3; NPHPL1; ICP55; X-Prolyl Aminopeptidase 3, Mitochondrial; Intermediate Cleaving Peptidase 55; Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; X-Prolyl Aminopeptidase (Aminopeptidase P) 3, Putative; Probable Xaa-Pro Aminopeptidase 3; Aminopeptidase P3; EC 3.4.11.9 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.01% Thimerosal and 50% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | XPNPEP3 |
| Gene Full Name | X-Prolyl Aminopeptidase 3 |
| Background | The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known. |
| Function | Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. |
| Cellular Localization | Cytoplasm, Mitochondrion |
| Calculated MW | 57 kDa |
Images (3) Click the Picture to Zoom In
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ARG44351 anti-XPNPEP3 antibody ICC/IF image
Immunofluorescence: L929 stained with ARG44351 anti-XPNPEP3 antibody at 1:100 dilution.
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ARG44351 anti-XPNPEP3 antibody WB image
Western blot: A562, A431 and 293 stained with ARG44351 anti-XPNPEP3 antibody at 1:1000 dilution.
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ARG44351 anti-XPNPEP3 antibody WB image
Western blot: Mouse kidney and Mouse heart stained with ARG44351 anti-XPNPEP3 antibody at 1:1000 dilution.
