ARG42117
anti-XPNPEP2 / mAPP antibody
anti-XPNPEP2 / mAPP antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes XPNPEP2 / mAPP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | XPNPEP2 / mAPP |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 22-240 of Human XPNPEP2 / mAPP (NP_003390.4). |
| Conjugation | Un-conjugated |
| Alternate Names | Membrane-bound aminopeptidase P; mAmP; APP2; AEACEI; Xaa-Pro aminopeptidase 2; Membrane-bound AmP; Aminoacylproline aminopeptidase; Membrane-bound APP; X-Pro aminopeptidase 2; EC 3.4.11.9 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | A549 | ||||
| Observed Size | ~ 76 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | XPNPEP2 |
| Gene Full Name | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| Background | Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008] |
| Function | Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin. [UniProt] |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
| Calculated MW | 76 kDa |
| PTM | N-glycosylated. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG42117 anti-XPNPEP2 / mAPP antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG42117 anti-XPNPEP2 / mAPP antibody at 1:1000 dilution.
