ARG59218
anti-Wnt2 antibody
anti-Wnt2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Wnt2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Wnt2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 56-81 of Human Wnt2. (HRHPDVMRAISQGVAEWTAECQHQFR) |
| Conjugation | Un-conjugated |
| Alternate Names | IRP; Int-1-related protein; INT1L1; Protein Wnt-2; Int-1-like protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | WNT2 |
| Gene Full Name | wingless-type MMTV integration site family member 2 |
| Background | This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. Secreted. [UniProt] |
| Calculated MW | 40 kDa |
| PTM | Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59218 anti-Wnt2 antibody WB image
Western blot: 40 µg of COLO320, MCF-7 and HeLa whole cell lysates stained with ARG59218 anti-Wnt2 antibody at 0.5 µg/ml dilution.
