ARG59214
anti-VNN1 / Vanin 1 antibody
anti-VNN1 / Vanin 1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes VNN1 / Vanin 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | VNN1 / Vanin 1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to Q22-K192 of Human VNN1. |
| Conjugation | Un-conjugated |
| Alternate Names | Tiff66; Vascular non-inflammatory molecule 1; EC 3.5.1.92; HDLCQ8; Pantetheinase; Pantetheine hydrolase; Vanin-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | VNN1 |
| Gene Full Name | vanin 1 |
| Background | This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009] |
| Function | Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. [UniProt] |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
| Calculated MW | 57 kDa |
Images (1) Click the Picture to Zoom In
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ARG59214 anti-VNN1 / Vanin 1 antibody WB image
Western blot: SKOV3 and HeLa whole cell lysates stained with ARG59214 anti-VNN1 / Vanin 1 antibody at 0.5 µg/ml dilution.
