ARG40768

anti-VIP antibody

anti-VIP antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Neuroscience antibody; Suprachiasmatic Nuclei (SCN) Study antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes VIP
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name VIP
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 81-107 of Human VIP. (HADGVFTSDFSKLLGQLSAKKYLESLM)
Conjugation Un-conjugated
Alternate Names Vasoactive intestinal polypeptide; PHM27; VIP peptides; Peptide histidine valine 42; VIP; Peptide histidine methioninamide 27

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:200 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 117064 Rat VIP

GeneID: 22353 Mouse VIP

GeneID: 7432 Human VIP

Gene Symbol VIP
Gene Full Name vasoactive intestinal peptide
Background The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
Function VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin. [UniProt]
Cellular Localization Secreted. [UniProt]
Research Area Neuroscience antibody; Suprachiasmatic Nuclei (SCN) Study antibody
Calculated MW 19 kDa

Images (3) Click the Picture to Zoom In

  • ARG40768 anti-VIP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse pancreas tissue stained with ARG40768 anti-VIP antibody at 1 µg/ml dilution.

  • ARG40768 anti-VIP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat pancreas tissue stained with ARG40768 anti-VIP antibody at 1 µg/ml dilution.

  • ARG40768 anti-VIP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human pancreatic cancer tissue stained with ARG40768 anti-VIP antibody at 1 µg/ml dilution.