ARG45379
anti-VEGF-B antibody [6E72]
anti-VEGF-B antibody [6E72] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [6E72] recognizes VEGF-B |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 6E72 |
| Isotype | IgG2 |
| Target Name | VEGF-B |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse VEGF-B. |
| Conjugation | Un-conjugated |
| Alternate Names | VEGFB; Vascular Endothelial Growth Factor B; VEGFL; VRF; VEGF-Related Factor; |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Powder |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Reconstitution | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P49766 Mouse Vascular endothelial growth factor B |
|---|---|
| Gene Symbol | VEGF-B |
| Gene Full Name | Vascular Endothelial Growth Factor B |
| Background | This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 22 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
-
ARG45379 anti-VEGF-B antibody [6E72] IHC-P image
Immunohistochemistry: Mouse lung stained with ARG45379 anti-VEGF-B antibody [6E72].
