ARG65014
anti-URP2 / kindlin 3 antibody
anti-URP2 / kindlin 3 antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes URP2 / kindlin 3 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Dog |
| Tested Application | WB |
| Specificity | This antibody is expected to recognize both isoforms (NP_113659.3, NP_848537.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | URP2 / kindlin 3 |
| Antigen Species | Human |
| Immunogen | C-ERARGEELDED |
| Conjugation | Un-conjugated |
| Alternate Names | URP2SF; Unc-112-related protein 2; KIND3; MIG2-like protein; UNC112C; MIG-2; Kindlin-3; URP2; MIG2B; Fermitin family homolog 3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 76 kDa |
Images (1) Click the Picture to Zoom In
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ARG65014 anti-URP2 / kindlin 3 antibody WB image
Western blot: Human Peripheral Blood Mononucleocytes lysate (35 µg protein in RIPA buffer) stained with ARG65014 anti-URP2 / kindlin 3 antibody at 1 µg/ml dilution.
