ARG54996
anti-URG4 antibody
anti-URG4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes URG4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | URG4 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 466-495 (Center) of Human URG4. |
| Conjugation | Un-conjugated |
| Alternate Names | URG4; HBxAg up-regulated gene 4 protein; Up-regulator of cell proliferation; HBV X protein up-regulated gene 4 protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | U-87 MG |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8TCY9 Human Up-regulator of cell proliferation |
|---|---|
| Gene Symbol | URGCP |
| Gene Full Name | upregulator of cell proliferation |
| Background | URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008] |
| Function | May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer. [UniProt] |
| Cellular Localization | Cytoplasm. Nucleus Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody |
| Calculated MW | 105 kDa |
Images (2) Click the Picture to Zoom In
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ARG54996 anti-URG4 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded brain tissue stained with ARG54996 anti-URG4 antibody.
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ARG54996 anti-URG4 antibody WB image
Western blot: 35 µg of U-87 MG cell lysate stained with ARG54996 anti-URG4 antibody at 1:1000 dilution.
