ARG44348
anti-UQCC2 / MNF1 antibody
anti-UQCC2 / MNF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes UQCC2 / MNF1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | UQCC2 / MNF1 |
| Antigen Species | Human |
| Immunogen | Human UQCC2 / MNF1 recombinant fusion protein (a.a. sequence: 14-126). |
| Conjugation | Un-conjugated |
| Alternate Names | UQCC2; Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2; Mitochondrial Nucleoid Factor 1; BA6B20.2; C6orf125; Cbp6; MNF1; M19; Breast Cancer-Associated Protein SGA-81M; Mitochondrial Protein M19; MGC14833; Cytochrome B Protein Synthesis 6 Homolog (S. Cerevisiae); Cytochrome B Protein Synthesis 6 Homolog; Chromosome 6 Open Reading Frame 125; C6orf126; MC3DN7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.02% sodium azide and 50% Glycerol. |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | UQCC2 |
| Gene Full Name | Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2 |
| Background | This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. |
| Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane, Mitochondrion nucleoid |
| Calculated MW | 15 kDa |
Images (6) Click the Picture to Zoom In
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ARG44348 anti-UQCC2 / MNF1 antibody WB image
Western blot: MCF7, THP-1 and HepG2 stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:1000 dilution.
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ARG44348 anti-UQCC2 / MNF1 antibody IHC-P image
Immunohistochemistry: Rat spleen stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:100 dilution.
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ARG44348 anti-UQCC2 / MNF1 antibody IHC-P image
Immunohistochemistry: Rat heart stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:100 dilution.
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ARG44348 anti-UQCC2 / MNF1 antibody WB image
Western blot: Rat brain stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:1000 dilution.
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ARG44348 anti-UQCC2 / MNF1 antibody IHC-P image
Immunohistochemistry: Mouse heart stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:100 dilution.
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ARG44348 anti-UQCC2 / MNF1 antibody WB image
Western blot: Mouse heart, Mouse brain stained with ARG44348 anti-UQCC2 / MNF1 antibody at 1:1000 dilution.
