ARG57074
anti-UGDH antibody [2G11]
anti-UGDH antibody [2G11] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [2G11] recognizes UGDH |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2G11 |
| Isotype | IgG2b, kappa |
| Target Name | UGDH |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-494 of Human UGDH. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 1.1.1.22; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UGD; UDPGDH; GDH |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | UGDH |
| Gene Full Name | UDP-glucose 6-dehydrogenase |
| Background | The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Function | Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. [UniProt] |
| Calculated MW | 55 kDa |
Images (1) Click the Picture to Zoom In
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ARG57074 anti-UGDH antibody [2G11] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) NIH-3T3 cell lysate, 3) HepG2 cell lysate, 4) A549 cell lysate, 5) MCF7 cell lysate stained with ARG57074 anti-UGDH antibody [2G11] at 1:1000.
