ARG64793
anti-U2AF1L4 antibody
anti-U2AF1L4 antibody for Western blot and Human
Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes U2AF1L4 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Dog |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_001035515.1 and NP_659424.2). No cross-reactivity with U2AF1 expected. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | U2AF1L4 |
| Antigen Species | Human |
| Immunogen | C-EDGERAVAELSNR |
| Conjugation | Un-conjugated |
| Alternate Names | RNU2; U2 auxiliary factor 26; U2AF1-like 4; Splicing factor U2AF 26 kDa subunit; U2; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1L3; U2AF1L3V1; U2AF1-like protein 3; U2af26; U2AF1RS3; U2AF1-RS3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WU68 Human Splicing factor U2AF 26 kDa subunit |
|---|---|
| Gene Symbol | U2AF1L4 |
| Gene Full Name | U2 small nuclear RNA auxiliary factor 1-like 4 |
| Function | RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). [UniProt] |
| Research Area | Gene Regulation antibody |
| Calculated MW | 26 kDa |
Images (1) Click the Picture to Zoom In
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ARG64793 anti-U2AF1L4 antibody WB image
Western Blot: Human Cerebellum lysate (35 µg protein in RIPA buffer) stained with ARG64793 anti-U2AF1L4 antibody at 0.1 µg/ml dilution.
