ARG64310
anti-Thyroid Hormone Receptor beta antibody
anti-Thyroid Hormone Receptor beta antibody for Western blot and Human
Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Thyroid Hormone Receptor beta |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Dog |
| Tested Application | WB |
| Specificity | This antibody is not expected to cross-react to THRA. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Thyroid Hormone Receptor beta |
| Antigen Species | Human |
| Immunogen | C-REELQKSIGHKP |
| Conjugation | Un-conjugated |
| Alternate Names | C-ERBA-2; NR1A2; THRB1; ERBA2; Nuclear receptor subfamily 1 group A member 2; GRTH; C-ERBA-BETA; c-erbA-2; Thyroid hormone receptor beta; PRTH; THRB2; c-erbA-beta; THR1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] |
| Research Area | Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 53 kDa |
Images (1) Click the Picture to Zoom In
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ARG64310 anti-Thyroid Hormone Receptor beta antibody WB image
Western blot: Human Bone Marrow lysate (35 µg protein in RIPA buffer) stained with ARG64310 anti-Thyroid Hormone Receptor beta antibody at 0.3 µg/ml dilution.
