ARG44763
anti-TXNDC5 / EndoPDI antibody
anti-TXNDC5 / EndoPDI antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes TXNDC5 / EndoPDI |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | TXNDC5 / EndoPDI |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | HCC2; ERp46; Thioredoxin domain-containing protein 5; HCC-2; Thioredoxin-like protein p46; UNQ364; ER protein 46; ERP46; PDIA15; ENDOPDI; STRF8; Endoplasmic reticulum resident protein 46 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8NBS9 Human Thioredoxin domain-containing protein 5 |
|---|---|
| Gene Symbol | TXNDC5 |
| Gene Full Name | thioredoxin domain containing 5 (endoplasmic reticulum) |
| Background | This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010] |
| Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. [UniProt] |
| Calculated MW | 50 kDa |
| PTM | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
Images (3) Click the Picture to Zoom In
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ARG44763 anti-TXNDC5 / EndoPDI antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44763 anti-TXNDC5 / EndoPDI antibody at 5 µg/mL dilution.
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ARG44763 anti-TXNDC5 / EndoPDI antibody WB image
Western blot: HepG2 stained with ARG44763 anti-TXNDC5 / EndoPDI antibody at 1 µg/mL dilution.
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ARG44763 anti-TXNDC5 / EndoPDI antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44763 anti-TXNDC5 / EndoPDI antibody.
