ARG44020
anti-TTBK1 antibody
anti-TTBK1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TTBK1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TTBK1 |
| Antigen Species | Human |
| Immunogen | Human TTBK1 recombinantprotein |
| Conjugation | Un-conjugated |
| Protein Full Name | Tau-tubulin kinase 1 |
| Alternate Names | TTBK1; Tau Tubulin Kinase 1; KIAA1855; Brain-Derived Tau Kinase; Tau-Tubulin Kinase 1; BDTK; EC 2.7.11.1; EC 2.7.11 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS containing 0.02% sodium azide |
| Preservative | 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TTBK1 |
| Gene Full Name | Tau Tubulin Kinase 1 |
| Background | Summary:This gene belongs to the casein kinase 1 superfamily. The encoded protein is a neuron-specific, serine/threonine and tyrosine kinase, which regulates phosphorylation of tau, a protein that associates with microtubule assemblies and stabilizes them. Genetic variants in this gene are associated with Alzheimer's disease. |
| Function | Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 143 kDa |
| PTM | Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG44020 anti-TTBK1 antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG44020 anti-TTBK1 antibody at 20 μg/mL dilution.
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ARG44020 anti-TTBK1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44020 anti-TTBK1 antibody at 2.5 μg/mL dilution.
