ARG10173

anti-TSH / Thyroid Stimulating Hormone antibody [TSH-1]

anti-TSH / Thyroid Stimulating Hormone antibody [TSH-1] for ELISA and Human

Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [TSH-1] recognizes TSH / Thyroid Stimulating Hormone
Tested Reactivity Hu
Tested Application ELISA
Host Mouse
Clonality Monoclonal
Clone TSH-1
Isotype IgG1, kappa
Target Name TSH / Thyroid Stimulating Hormone
Antigen Species Human
Immunogen Recombinant human TSH
Conjugation Un-conjugated
Alternate Names FSH-alpha; LSH-alpha; FSHA; Thyrotropin alpha chain; LHA; CG-alpha; GPHA1; TSHA; Chorionic gonadotrophin subunit alpha; Luteinizing hormone alpha chain; TSH-alpha; Choriogonadotropin alpha chain; GPHa; CG-ALPHA; Anterior pituitary glycoprotein hormones common subunit alpha; Follitropin alpha chain; HCG; Glycoprotein hormones alpha chain; Thyroid-stimulating hormone alpha chain; Follicle-stimulating hormone alpha chain; Lutropin alpha chain

Application Instructions

Application Note ELISA: This antibody can be used as capture antibody in sandwich ELISA for human TSH detection in combination with HRP conjugated TSHβ antibody (Cat No: ARG10174). The suggested capturer coating quantity is 4μg/mL.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2)
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1081 Human CGA

Swiss-port # P01215 Human Glycoprotein hormones alpha chain

Gene Symbol CGA
Gene Full Name glycoprotein hormones, alpha polypeptide
Background Thyroid stimulation hormone is secreted by pituitary gland in response to the stimulation of Thyrotropin Releasing Hormone (TRH) produced by hypothalamus. TSH binds to the TSH receptors on the surface of the follicular cells in thyroid and stimulates the production of thyroid hormones (T4 and T3). TSH, T3 and T4 play an important role in normal growth, brain development in young children, and regulate the metabolism in adults. TSH secretion is increased when T3 and T4 are insufficient. Elevated TSH, but low T3 and T4 levels indicate that thyroid cannot produce thyroid hormones at a normal rate and the condition is called hypothyroidism. If T3 and T4 levels are high when TSH is at a low level, it indicates that thyroid is producing abnormally large amount thyroid hormones, and the condition is called hyperthyroidism which is manifested by hypermetabolic symptoms. TSH has a α subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.
Highlight Related Antibody Duos and Panels:
ARG30056 TSH / Thyroid Stimulating Hormone ELISA Antibody Duo
Related products:
TSH antibodies; TSH ELISA Kits; TSH Duos / Panels; Anti-Mouse IgG secondary antibodies;
Research Area Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 13 kDa