ARG64910
anti-TRPC7 antibody
anti-TRPC7 antibody for Immunoprecipitation,Western blot and Chicken
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TRPC7 |
|---|---|
| Tested Reactivity | Chk |
| Predict Reactivity | Hu, Ms, Rat, Dog |
| Tested Application | IP, WB |
| Specificity | This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRPC7 |
| Antigen Species | Human |
| Immunogen | KLCKSKAKSCEND |
| Conjugation | Un-conjugated |
| Alternate Names | hTRP7; Transient receptor protein 7; TrpC7; Short transient receptor potential channel 7; TRP-7; TRP7 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TRPC7 |
|---|---|
| Gene Full Name | transient receptor potential cation channel, subfamily C, member 7 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. [UniProt] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 100 kDa |
| PTM | Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity. |
