ARG64957
anti-TRPC4AP antibody
anti-TRPC4AP antibody for Western blot and Human
Gene Regulation antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TRPC4AP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_955400.1; NP_056453.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRPC4AP |
| Antigen Species | Human |
| Immunogen | C-KLTQETTYPNTYIFD |
| Conjugation | Un-conjugated |
| Alternate Names | TRRP4AP; PPP1R158; Trpc4-associated protein; Protein TRUSS; C20orf188; Protein TAP1; Short transient receptor potential channel 4-associated protein; Trp4-associated protein; TNF-receptor ubiquitous scaffolding/signaling protein; TRUSS |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8TEL6 Human Short transient receptor potential channel 4-associated protein |
|---|---|
| Gene Symbol | TRPC4AP |
| Gene Full Name | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| Function | Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. [UniProt] |
| Research Area | Gene Regulation antibody; Signaling Transduction antibody |
| Calculated MW | 91 kDa |
Images (1) Click the Picture to Zoom In
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ARG64957 anti-TRPC4AP antibody WB image
Western Blot: U937 lysate (35 µg protein in RIPA buffer) stained with ARG64957 anti-TRPC4AP antibody at 1 µg/ml dilution.
