ARG63271
anti-TRIM63 / MuRF1 antibody
anti-TRIM63 / MuRF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TRIM63 / MuRF1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Dog |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRIM63 / MuRF1 |
| Antigen Species | Human |
| Immunogen | DYKSSLIQDGNPM-C |
| Conjugation | Un-conjugated |
| Alternate Names | E3 ubiquitin-protein ligase TRIM63; Muscle-specific RING finger protein 1; EC 6.3.2.-; MURF2; MURF1; MuRF-1; Striated muscle RING zinc finger protein; SMRZ; RNF28; RING finger protein 28; Tripartite motif-containing protein 63; MuRF1; IRF; Iris RING finger protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q969Q1 Human E3 ubiquitin-protein ligase TRIM63 |
|---|---|
| Background | This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012] |
| Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
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ARG63271 anti-TRIM63 / MuRF1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human skeletal muscle (steamed antigen retrieval with citrate buffer pH 6.0) stained with ARG63271 anti-TRIM63 / MuRF1 antibody at 1.25 µg/ml dilution followed by AP-staining.
