ARG59863

anti-TRH / Thyrotropin Releasing Hormone antibody

anti-TRH / Thyrotropin Releasing Hormone antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes TRH / Thyrotropin Releasing Hormone
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TRH / Thyrotropin Releasing Hormone
Antigen Species Human
Immunogen Synthetic peptide within aa. 100-200 of Human TRH (NP_009048.1).
Conjugation Un-conjugated
Alternate Names TRH; Thyroliberin; Pro-thyrotropin-releasing hormone; Protirelin; Prothyroliberin; Thyrotropin-releasing factor; TRF; TSH-releasing factor; Pro-TRH

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat testis, Mouse brain and A549
Observed Size 27 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 22044 Mouse TRH

GeneID: 25569 Rat TRH

GeneID: 7200 Human TRH

Gene Symbol TRH
Gene Full Name thyrotropin-releasing hormone
Background This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
Function Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 27 kDa

Images (1) Click the Picture to Zoom In

  • ARG59863 anti-TRH / Thyrotropin Releasing Hormone antibody WB image

    Western blot: 25 µg of Rat testis, Mouse brain and A549 cell lysates stained with ARG59863 anti-TRH / Thyrotropin Releasing Hormone antibody at 1:3000 dilution.