ARG11172
anti-TREK1 antibody
anti-TREK1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TREK1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TREK1 |
| Antigen Species | Human |
| Immunogen | A synthetic peptide (SASRERPGYTA) derived from the amino acid residue 4-14 of human TREK-1, conjugated with KLH for immunization. |
| Conjugation | Un-conjugated |
| Alternate Names | KCNH2; Potassium Voltage-Gated Channel Subfamily H Member 2; HERG 2; Kv11.1; Erg1; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Voltage-Gated Inwardly Rectifying Potassium Channel KCNH2; Ether-A-Go-Go-Related Gene Potassium Channel 1; Voltage-Gated Potassium Channel Subunit Kv11.1; Ether-A-Go-Go-Related Protein 1; Long QT Syndrome Type 2; Eag-Related Protein 1; Eag Homolog; ERG-1; H-ERG; HERG1; LQT2; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 2; Ether-A-Go-Go-Related Potassium Channel Protein; Human Ether-A-Go-Go-Related Gene; Human Ether-A-Go-Go-Related; HERG-1; SQT1; ERG1; ERG |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.4) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95069 Human Potassium channel subfamily K member 2 |
|---|---|
| Gene Symbol | KCNK2 |
| Gene Full Name | Potassium Two Pore Domain Channel Subfamily K Member 2 |
| Background | This gene encodes a component of a voltage-activated potassium channel found in cardiac muscle, nerve cells, and microglia. Four copies of this protein interact with one copy of the KCNE2 protein to form a functional potassium channel. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, May 2022] |
| Function | Forms a stable complex with KCNE1 or KCNE2, and that this heteromultimerization regulates inward rectifier potassium channel activity. [UniProt] |
| Cellular Localization | Cell membrane, Membrane. [UniProt] |
| Calculated MW | 127 kDa |
| PTM | Glycoprotein, Methylation, Phosphoprotein. [UniProt] |
