ARG64377
anti-TMPRSS3 antibody
anti-TMPRSS3 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TMPRSS3 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1) |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMPRSS3 |
| Antigen Species | Human |
| Immunogen | C-EKIVYHSKYKPKR |
| Conjugation | Un-conjugated |
| Alternate Names | ECHOS1; Transmembrane protease serine 3; DFNB10; Tumor-associated differentially-expressed gene 12 protein; DFNB8; TADG12; EC 3.4.21.-; Serine protease TADG-12 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] |
| Research Area | Cell Biology and Cellular Response antibody; Neuroscience antibody |
| Calculated MW | 49 kDa |
| PTM | Undergoes autoproteolytic activation. |
Images (1) Click the Picture to Zoom In
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ARG64377 anti-TMPRSS3 antibody WB image
Western Blot: A431 cell lysate (35 µg protein in RIPA buffer) stained with ARG64377 anti-TMPRSS3 antibody at 0.1 µg/ml dilution.
