ARG65005

anti-TLN1 / Talin 1 antibody

anti-TLN1 / Talin 1 antibody for Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes TLN1 / Talin 1
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application WB
Specificity This antibody is not expected to cross-react with the highly similar protein Talin 2.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name TLN1 / Talin 1
Antigen Species Human
Immunogen C-QEALHTQMLTAVQE
Conjugation Un-conjugated
Alternate Names Talin-1; TLN; ILWEQ

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7094 Human TLN1

Swiss-port # Q9Y490 Human Talin-1

Background This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
Research Area Signaling Transduction antibody
Calculated MW 270 kDa

Images (1) Click the Picture to Zoom In

  • ARG65005 anti-TLN1 / Talin 1 antibody WB image

    Western blot: Human Peripheral Mononucleocytes lysate (35 µg protein in RIPA buffer) stained with ARG65005 anti-TLN1 / Talin 1 antibody at 1 µg/ml dilution.