ARG63431
anti-TIP30 / CC3 antibody
anti-TIP30 / CC3 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Microbiology and Infectious Disease antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TIP30 / CC3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise all three reported isoforms. Variants (NP_006401.3; NP_001091991.1; NP_001091992.1) encode the same isoform. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TIP30 / CC3 |
| Antigen Species | Human |
| Immunogen | AETEALSKLREDFR-C |
| Conjugation | Un-conjugated |
| Alternate Names | Oxidoreductase HTATIP2; CC3; TIP30; EC 1.1.1.-; HIV-1 TAT-interactive protein 2; 30 kDa HIV-1 TAT-interacting protein; SDR44U1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HTATIP2 |
| Gene Full Name | HIV-1 Tat interactive protein 2, 30kDa |
| Function | Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Microbiology and Infectious Disease antibody; Signaling Transduction antibody |
| Calculated MW | 27 kDa |
Images (1) Click the Picture to Zoom In
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ARG63431 anti-TIP30 / CC3 antibody WB image
Western Blot: HeLa lysate (35 µg protein in RIPA buffer) stained with ARG63431 anti-TIP30 antibody at 0.6 µg/ml dilution.
