ARG22193
anti-TIMP4 antibody [SB30c]
anti-TIMP4 antibody [SB30c] for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [SB30c] recognizes TIMP4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, ICC/IF, IHC-P, WB |
| Specificity | Human/Mouse/Rat TIMP-4 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SB30c |
| Isotype | IgG2a, kappa |
| Target Name | TIMP4 |
| Antigen Species | Human |
| Immunogen | Recombinant Human TIMP-4 (a.a. 35-224) |
| Conjugation | Un-conjugated |
| Alternate Names | Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | BBS (pH 8.2) |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TIMP4 |
| Gene Full Name | TIMP metallopeptidase inhibitor 4 |
| Background | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008] |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. [UniProt] |
| Calculated MW | 26 kDa |
Images (2) Click the Picture to Zoom In
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ARG22193 anti-TIMP4 antibody [SB30c] ICC/IF image
Immunofluorescence: Human pancreatic carcinoma cell line MIA PaCa-2 stained with ARG22193 anti-TIMP4 antibody [SB30c] followed by ARG23776 Goat anti-Mouse IgA + IgG + IgM antibody (FITC) (pre-adsorbed) and DAPI.
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ARG22193 anti-TIMP4 antibody [SB30c] IHC-P image
Immunohistochemistry: Paraffin-embedded Human gastric cancer tissue stained with ARG22193 anti-TIMP4 antibody [SB30c] (right) followed by HRP-conjugated anti-Mouse Ig secondary antibody, DAB and hematoxylin.
