ARG44959

anti-THOC6 / WDR58 antibody

anti-THOC6 / WDR58 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody recognizes THOC6 / WDR58
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name THOC6 / WDR58
Antigen Species Human
Conjugation Un-conjugated
Alternate Names THOC6; THO Complex Subunit 6; FSAP35; Functional Spliceosome-Associated Protein 35; WDR58; WD Repeat-Containing Protein 58; THO Complex Subunit 6 Homolog; WD Repeat Domain 58; THO Complex 6; MGC2655; THO Complex 6 Homolog (Drosophila); MMRFCGU

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 79228 Human THOC6

Swiss-port # Q86W42 Human THO complex subunit 6 homolog

Gene Symbol THOC6
Gene Full Name THO Complex Subunit 6
Background This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016]
Function Plays a role in apoptosis negative control involved in brain development. [UniProt]
Cellular Localization Nucleus. [UniProt]
PTM Phosphoprotein. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG44959 anti-THOC6 / WDR58 antibody IHC-P image

    Immunohistochemistry: Human colon cancer stained with ARG44959 anti-THOC6 / WDR58 antibody at 10 µg/mL dilution.

  • ARG44959 anti-THOC6 / WDR58 antibody WB image

    Western blot: A549 stained with ARG44959 anti-THOC6 / WDR58 antibody at 1 µg/mL dilution.