ARG10593

Name: anti-TGM2 / Tissue transglutaminase antibody
Brand: arigo Biolaboratories
SKU: ARG10593
Price: 325 USD
Availability: InStock
Rating: 3.0 (1 reviews)

anti-TGM2 / Tissue transglutaminase antibody

Datasheet

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Price (USD)

50 μg

325.00

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Datasheet
Review (1)

Overview

Product Description	Rabbit Polyclonal antibody recognizes TGM2 / Tissue transglutaminase
Tested Reactivity	Hu, Ms, Rat
Tested Application	IHC-Fr, IHC-P, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	TGM2 / Tissue transglutaminase
Antigen Species	Human
Immunogen	Synthetic peptide derived from Human TGM2 / Tissue transglutaminase protein: LERCDLELETNGRDHHTADLCREKLVVR
Conjugation	Un-conjugated
Alternate Names	TG2; G-ALPHA-h; TGase H; Transglutaminase C; TGase C; HEL-S-45; Transglutaminase-2; Tissue transglutaminase; C; TGase-2; TGC; Protein-glutamine gamma-glutamyltransferase 2; TG; Transglutaminase H; GNAH; EC 2.3.2.13

Application Instructions

Application Suggestion

Tested Application	Dilution
IHC-Fr	0.5 - 1 µg/ml
IHC-P	0.5 - 1 µg/ml
WB	0.5 - 1 µg/ml

Application Note

Antigen retrieval for IHC-P: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	1X PBS, 0.025% Sodium azide and 2.5% BSA
Preservative	0.025% Sodium azide
Stabilizer	2.5% BSA
Concentration	0.5 mg/ml
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 21817 Mouse TGM2 GeneID: 7052 Human TGM2 Swiss-port # P21980 Human Protein-glutamine gamma-glutamyltransferase 2 Swiss-port # P21981 Mouse Protein-glutamine gamma-glutamyltransferase 2
Gene Symbol	TGM2
Gene Full Name	transglutaminase 2
Background	Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function	Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. [UniProt]
Calculated MW	77 kDa

Images (8) Click the Picture to Zoom In

ARG10593 anti-TGM2 antibody IHC-P image

Immunohistochemistry: Human intestine cancer stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody WB image

Western blot: 1) Rat liver, 2) Rat ovary, and 3) HeLa cell lysate stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-P image

Immunohistochemistry: Human breast cancer stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-Fr image

Immunohistochemistry: Human placental tissue stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-P image

Immunohistochemistry: Mouse spleen tissue stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-Fr image

Immunohistochemistry: Mouse spleen tissue stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-P image

Immunohistochemistry: Rat spleen tissue stained with ARG10593 anti-TGM2 antibody.
ARG10593 anti-TGM2 antibody IHC-Fr image

Immunohistochemistry: Rat spleen tissue stained with ARG10593 anti-TGM2 antibody.