ARG42053
anti-TGFBR3 antibody
anti-TGFBR3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TGFBR3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TGFBR3 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide around the C-terminal region of Human TGFBR3. |
| Conjugation | Un-conjugated |
| Alternate Names | TGF-beta receptor type 3; Transforming growth factor beta receptor type 3; BGCAN; Betaglycan; TGF-beta receptor type III; betaglycan; TGFR-3; Transforming growth factor beta receptor III |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 93 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 30% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O88393 Mouse Transforming growth factor beta receptor type 3 Swiss-port # Q03167 Human Transforming growth factor beta receptor type 3 |
|---|---|
| Gene Symbol | TGFBR3 |
| Gene Full Name | transforming growth factor, beta receptor III |
| Function | Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. [UniProt] |
| Cellular Localization | Secreted. Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. [UniProt] |
| Calculated MW | 93 kDa |
| PTM | Extensively modified by glycosaminoglycan groups (GAG). [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG42053 anti-TGFBR3 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human placenta tissue. Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). The section was then stained with ARG42053 anti-TGFBR3 antibody at room temperature. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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ARG42053 anti-TGFBR3 antibody WB image
Western blot: Mouse kidney, Mouse heart, Mouse brain and Mouse lung lysates stained with ARG42053 anti-TGFBR3 antibody.
