ARG56267

anti-TBXAS1 antibody

anti-TBXAS1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes TBXAS1
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TBXAS1
Antigen Species Human
Immunogen Recombinant protein of Human TBXAS1
Conjugation Un-conjugated
Alternate Names THAS; Thromboxane-A synthase; EC 5.3.99.5; Cytochrome P450 5A1; TXA synthase; TS; CYP5A1; TXAS; CYP5; BDPLT14; GHOSAL; TXS

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control U937

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 21391 Mouse TBXAS1

GeneID: 24886 Rat TBXAS1

GeneID: 6916 Human TBXAS1

Gene Symbol TBXAS1
Gene Full Name thromboxane A synthase 1 (platelet)
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Calculated MW 61 kDa

Images (2) Click the Picture to Zoom In

  • ARG56267 anti-TBXAS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse heart stained with ARG56267 anti-TBXAS1 antibody at 1:100 dilution.

  • ARG56267 anti-TBXAS1 antibody WB image

    Western blot: U937 cell lysate stained with ARG56267 anti-TBXAS1 antibody.