ARG41261
anti-Syntaxin 8 antibody
anti-Syntaxin 8 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Syntaxin 8 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Gpig, Hrs, Zfsh |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Syntaxin 8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide located within the following region: ISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRKS |
| Conjugation | Un-conjugated |
| Alternate Names | CARB; Syntaxin-8 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 93%; Guinea pig: 100%; Horse: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100% | ||||
|---|---|---|---|---|---|
| Application Suggestion |
|
||||
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human fetal heart | ||||
| Observed Size | 29 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | STX8 |
| Gene Full Name | syntaxin 8 |
| Background | The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| Function | Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. [UniProt] |
| Cellular Localization | Membrane; Single-pass type IV membrane protein. Note=Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity). [UniProt] |
| Calculated MW | 27 kDa |
| PTM | Ubiquitinated by HECTD3. [UniProt] |
Images (1) Click the Picture to Zoom In
-
ARG41261 anti-Syntaxin 8 antibody WB image
Western blot: Human fetal heart lysate stained with ARG41261 anti-Syntaxin 8 antibody at 1 µg/ml dilution.
