ARG64578
anti-Sterol carrier protein 2 antibody
anti-Sterol carrier protein 2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Sterol carrier protein 2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig |
| Tested Application | IHC-P |
| Specificity | This antibody is expected to recognize isoform 1, 2, 6, 7 and 8 (NP_002970.2; NP_001007099.1; NP_001180529.1; NP_001180528.1; NP_001180546.1 respectively), |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Sterol carrier protein 2 |
| Antigen Species | Human |
| Immunogen | C-KNHKHSVNNPYSQ |
| Conjugation | Un-conjugated |
| Alternate Names | SCP-CHI; EC 2.3.1.176; NSL-TP; NLTP; SCPX; Non-specific lipid-transfer protein; Sterol carrier protein 2; Sterol carrier protein X; SCP-2; SCP-chi; Propanoyl-CoA C-acyltransferase; SCP-X |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P22307 Human Non-specific lipid-transfer protein |
|---|---|
| Background | This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010] |
| Research Area | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 59 kDa |
Images (1) Click the Picture to Zoom In
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ARG64578 anti-Sterol carrier protein 2 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Liver-. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64578 anti-Sterol carrier protein 2 antibody at 3.8 µg/ml dilution followed by AP-staining.
