ARG67072
anti-StAR antibody [SQab30347]
anti-StAR antibody [SQab30347] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab30347] recognizes StAR |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30347 |
| Target Name | StAR |
| Antigen Species | Human |
| Immunogen | Recombinant protein fragment of StAR |
| Conjugation | Un-conjugated |
| Protein Full Name | StAR |
| Alternate Names | STAR; Steroidogenic Acute Regulatory Protein; STARD1; StAR Related Lipid Transfer (START) Domain Containing 1; Steroidogenic Acute Regulatory Protein, Mitochondrial; START Domain-Containing Protein 1; Steroidogenic Acute Regulator; Testis Secretory Sperm-Binding Protein Li 241mP; Mitochondrial Steroid Acute Regulatory Protein; Steroid Acute Regulatory Protein; START Domain Containing 1; Cholesterol Trafficker; StARD1; StAR |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | -20°C |
| Note | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # P49675 Human Steroidogenic acute regulatory protein, mitochondrial |
|---|---|
| Gene Symbol | STAR |
| Gene Full Name | steroidogenic acute regulatory protein |
| Background | The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008] |
| Function | Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 32 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
-
ARG67072 anti-StAR antibody [SQab30347] IHC-P image
Immunohistochemistry: Human adrenocortical adenoma tissue stained with ARG67072 anti-StAR antibody [SQab30347] at 1:100 dilution.
