ARG44936

anti-Spermine Synthase antibody

anti-Spermine Synthase antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human

Overview

Product Description Mouse Monoclonal antibody recognizes Spermine Synthase
Tested Reactivity Hu
Tested Application IHC-P, IP
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name Spermine Synthase
Antigen Species Human
Epitope MAAARHSTLD FMLGAKADGE TILKGLQSIF QEQGMAESVH TWQDHGYLAT YTNKNGSFAN LRIYPHGLVL LDLQSYDGDA QGKEEIDSIL NKVEERMKEL SQDSTGRVKR LPPIVRGGAI DRYWPTADGR LVEYDIDEVV YDEDSPYQNI KILHSKQFGN ILILSGDVNL AESDLAYTRA IMGSGKEDYT GKDVLILGGG DGGILCEIVK LKPKMVTMVE IDQMVIDGCK KYMRKTCGDV LDNLKGDCYQ VLIEDCIPVL KRYAKEGREF DYVINDLTAV PISTSPEEDS TWEFLRLILD LSMKVLKQDG KYFTQGNCVN LTEALSLYEE QLGRLYCPVE FSKEIVCVPS YLELWVFYTV WKKAKP
Conjugation Un-conjugated
Alternate Names SMS; Spermine Synthase; SPMSY; MRSR; SpS; Spermidine Aminopropyltransferase; SRS; Snyder-Robinson X-Linked Mental Retardation Syndrome; EC 2.5.1.22; MRXSSR

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:250 - 1:500
IP1:100
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6611 Human SMS

Swiss-port # P52788 Human Spermine synthase

Gene Symbol SMS
Gene Full Name Spermine Synthase
Background This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Function Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). [UniProt]
PTM Acetylation, Phosphoprotein. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG44936 anti-Spermine Synthase antibody IHC-P image

    Immunohistochemistry: Human testis stained with ARG44936 anti-Spermine Synthase antibody at 2.5 µg/mL dilution.

  • ARG44936 anti-Spermine Synthase antibody IP image

    Immunoprecipitation: A375 lysate immunoprecipitated with 2.5 µg of ARG44936 anti-Spermine Synthase antibody.