ARG45083
anti-Semaphorin 4D antibody [M188]
anti-Semaphorin 4D antibody [M188] for Western blot,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Mouse Monoclonal antibody [M188] recognizes Semaphorin 4D |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | M188 |
| Isotype | IgG1 |
| Target Name | Semaphorin 4D |
| Antigen Species | Human |
| Immunogen | Clone (M188) was generated from a recombinant protein corresponding to the C-terminal region of human Semaphorin-4D. |
| Conjugation | Un-conjugated |
| Alternate Names | SEMA4D; Semaphorin 4D; CD100; C9orf164; Coll-4; SEMAJ; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 4D; Semaphorin-4D; FLJ39737; BB18; GR3 ; A8; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, 4D; Chromosome 9 Open Reading Frame 164; CD100 Antigen; M-Sema G; M-Sema-G; COLL4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G Purified. |
| Buffer | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| Stabilizer | 50% Glycerol and 0.1 % BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SEMA4D |
| Gene Full Name | Semaphorin 4D |
| Background | Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of neuron projection development; and regulation of phosphate metabolic process. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| Calculated MW | 96 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG45083 anti-Semaphorin 4D antibody [M188] ICC/IF image
Immunofluorescence: PC12 stained with ARG45083 anti-Semaphorin 4D antibody [M188].
