ARG66933
anti-Sall4 antibody [SQab22262]
anti-Sall4 antibody [SQab22262] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab22262] recognizes Sall4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab22262 |
| Isotype | IgG |
| Target Name | Sall4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within Human Sall4. |
| Conjugation | Un-conjugated |
| Protein Full Name | Sal-like protein 4 |
| Alternate Names | dJ1112F19.1; Zinc finger protein 797; DRRS; Zinc finger protein SALL4; Sal-like protein 4; HSAL4; ZNF797 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Human seminoma tissue |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05%BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SALL4 |
| Gene Full Name | spalt-like transcription factor 4 |
| Background | The protein encoded by this gene may be a zinc finger transcription factor. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). [provided by RefSeq, Jul 2008] |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. [UniProt] |
| Cellular Localization | Cytoplasm. Nucleus. [UniProt] |
| Calculated MW | 112 kDa |
| PTM | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG66933 anti-Sall4 antibody [SQab22262] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human seminoma tissue stained with ARG66933 anti-Sall4 antibody [SQab22262]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).
