ARG63628
anti-STMN2 / SCG10 antibody
anti-STMN2 / SCG10 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes STMN2 / SCG10 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu, Rat, Cow, Dog |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STMN2 / SCG10 |
| Antigen Species | Human |
| Immunogen | AKTAMAYKEK-C |
| Conjugation | Un-conjugated |
| Alternate Names | Protein SCG10; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010] |
| Research Area | Neuroscience antibody |
| Calculated MW | 21 kDa |
| PTM | Sumoylated. Phosphorylated mostly by MAPK8, but also by MAPK9 and MAPK10 in the developing brain cortex. N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15. |
Images (3) Click the Picture to Zoom In
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ARG63628 anti-STMN2 / SCG10 antibody WB image
Western Blot: Human Brain lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63628 anti-STMN2 / SCG10 antibody at 1 µg/ml dilution.
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ARG63628 anti-STMN2 / SCG10 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63628 anti-STMN2 / SCG10 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG63628 anti-STMN2 / SCG10 antibody WB image
Western blot: 35 µg of Mouse foetal brain lysate (in RIPA buffer) stained with ARG63628 anti-STMN2 / SCG10 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.
