ARG66901
anti-STK38 / NDR1 antibody
anti-STK38 / NDR1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes STK38 / NDR1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STK38 / NDR1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide between aa. 390-470 of Human STK38 / NDR1. |
| Conjugation | Un-conjugated |
| Alternate Names | Nuclear Dbf2-related kinase 1; NDR1 protein kinase; Serine/threonine-protein kinase 38; EC 2.7.11.1; NDR; NDR1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HCT116 | ||||
| Observed Size | ~ 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15208 Human Serine/threonine-protein kinase 38 |
|---|---|
| Gene Symbol | STK38 |
| Gene Full Name | serine/threonine kinase 38 |
| Background | This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
| Function | Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. [UniProt] |
| Calculated MW | 54 kDa |
| PTM | ISGylated. Phosphorylated by STK3/MST2 and this is enhanced by MOBKL1B. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG66901 anti-STK38 / NDR1 antibody WB image
Western blot: HCT116 cell lysate stained with ARG66901 anti-STK38 / NDR1 antibody at 1:1000 dilution, overnight at 4°C.
