ARG59088
anti-SOX5 antibody
anti-SOX5 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SOX5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SOX5 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-120 of Human SOX5 (NP_694534.1). |
| Conjugation | Un-conjugated |
| Alternate Names | L-SOX5B; L-SOX5; Transcription factor SOX-5; L-SOX5F |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 70kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SOX5 |
| Gene Full Name | SRY (sex determining region Y)-box 5 |
| Background | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 84 kDa |
Images (2) Click the Picture to Zoom In
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ARG59088 anti-SOX5 antibody ICC/IF image
Immunofluorescence: MCF7 cells stained with ARG59088 anti-SOX5 antibody.
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ARG59088 anti-SOX5 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon carcinoma stained with ARG59088 anti-SOX5 antibody at 1:100 dilution.
