ARG63327

anti-SORBS1 / Ponsin antibody

anti-SORBS1 / Ponsin antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes SORBS1 / Ponsin
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Pig
Tested Application IHC-P
Specificity This antibody is expected to recognize all seven reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name SORBS1 / Ponsin
Antigen Species Human
Immunogen C-GTFPGNYVKPLYL
Conjugation Un-conjugated
Alternate Names SORB1; Sorbin and SH3 domain-containing protein 1; c-Cbl-associated protein; CAP; Ponsin; SH3 domain protein 5; FLAF2; SH3P12; R85FL; SH3D5

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2.5 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10580 Human SORBS1

Swiss-port # Q9BX66 Human Sorbin and SH3 domain-containing protein 1

Background This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Research Area Signaling Transduction antibody
Calculated MW 143 kDa
PTM O-glycosylated.

Images (1) Click the Picture to Zoom In

  • ARG63327 anti-SORBS1 / Ponsin antibody IHC-P image

    Immunohistochemistry: paraffin embedded human skeletal muscle. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63327 anti-SORBS1 / Ponsin antibody at 2.5 µg/ml dilution followed by AP-staining.