ARG22356
anti-SMO / Smoothened Homolog antibody
anti-SMO / Smoothened Homolog antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SMO / Smoothened Homolog |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SMO / Smoothened Homolog |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human SMO / Smoothened Homolog. |
| Conjugation | Un-conjugated |
| Alternate Names | Gx; SMO; Protein Gx; Smoothened homolog; FZD11; SMOH |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human brain. |
Properties
| Form | Liquid |
|---|---|
| Purification | Ammonium sulfate precipitation. |
| Buffer | PBS and 0.08% Sodium azide. |
| Preservative | 0.08% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SMO |
| Gene Full Name | smoothened, frizzled class receptor |
| Background | The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] |
| Function | G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. [UniProt] |
| Calculated MW | 86 kDa |
Images (1) Click the Picture to Zoom In
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ARG22356 anti-SMO / Smoothened Homolog antibody WB image
Western blot: 15 µg of Human brain lysate stained with ARG22356 anti-SMO / Smoothened Homolog antibody at 1) 10 µg/ml, and 2) 5 µg/ml dilution.
