ARG57586
anti-SLC47A2 / MATE2 antibody
anti-SLC47A2 / MATE2 antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC47A2 / MATE2 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC47A2 / MATE2 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 125-153 (N-terminus) of Human SLC47A2 / MATE2. |
| Conjugation | Un-conjugated |
| Alternate Names | Kidney-specific H; Multidrug and toxin extrusion protein 2; MATE2K; MATE-2; MATE2; MATE2-K; hMATE-2; Solute carrier family 47 member 2; MATE2-B |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse kidney |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q3V050 Mouse Multidrug and toxin extrusion protein 2 |
|---|---|
| Gene Symbol | SLC47A2 |
| Gene Full Name | solute carrier family 47 (multidrug and toxin extrusion), member 2 |
| Background | This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules |
| Calculated MW | 65 kDa |
Images (1) Click the Picture to Zoom In
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ARG57586 anti-SLC47A2 / MATE2 antibody WB image
Western blot: 35 µg of Mouse kidney lysate stained with ARG57586 anti-SLC47A2 / MATE2 antibody.
