ARG66410
anti-SLC16A3 / MCT4 antibody
anti-SLC16A3 / MCT4 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC16A3 / MCT4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC16A3 / MCT4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 210-290 of Human SLC16A3 / MCT4. |
| Conjugation | Un-conjugated |
| Alternate Names | MCT 4; MCT 3; Solute carrier family 16 member 3; Monocarboxylate transporter 4; MCT4; MCT-3; MCT-4; MCT3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | ~ 47 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SLC16A3 |
| Gene Full Name | solute carrier family 16 (monocarboxylate transporter), member 3 |
| Background | Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008] |
| Function | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 49 kDa |
Images (2) Click the Picture to Zoom In
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ARG66410 anti-SLC16A3 / MCT4 antibody WB image
Western blot: LOVO cell lysate stained with ARG66410 anti-SLC16A3 / MCT4 antibody at 1:500 dilution.
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ARG66410 anti-SLC16A3 / MCT4 antibody WB image
Western blot: PC-3 cell lysate stained with ARG66410 anti-SLC16A3 / MCT4 antibody at 1:500 dilution.
